What’s the correct setup for hooking up an spm4649t, a dsmx sat, and Hobbywing telemetry into a Spirit 2?

I know you need a Jeti cable for the receiver, and the Hobbywing telem goes into the primary sat port. Will the satellite plugged into the secondary sat port work?

The manual states:

“If you want to use only one satellite, you have to use the Primary (SAT-1) connector.”

In this case, there’s only one “satellite”, but the primary port is occupied by the telem cable.

Or does that statement not apply since there is already another receiver present (the 4649t)?

Yes, the sat can go into the secondary port.